GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs10935120 | 1 | rs9289475 | chr3:134236459 | ANAPC13 | chr3:134196547-134204865:- | 0.58 | 8.01 | 2.88E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs9289475 | chr3:134236459 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 6.04 | 2.93E-8 | Height |
| THYM | cis | rs10935120 | 1 | rs9289476 | chr3:134237103 | ANAPC13 | chr3:134196547-134204865:- | 0.56 | 7.61 | 1.94E-11 | Height |
| THYM | cis | rs10935120 | 1 | rs9289476 | chr3:134237103 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 6 | 3.54E-8 | Height |
| THYM | cis | rs10935120 | 1 | rs9289478 | chr3:134268619 | ANAPC13 | chr3:134196547-134204865:- | 0.56 | 7.61 | 1.94E-11 | Height |
| THYM | cis | rs10935120 | 1 | rs9289478 | chr3:134268619 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 6 | 3.54E-8 | Height |
| THYM | cis | rs9362426 | 1 | rs9294377 | chr6:88084839 | C6orf164 | chr6:88032306-88109459:+ | -0.5 | -4.99 | 2.68E-6 | Depressive episodes in bipolar disorder |
| THYM | cis | rs9296404 | 1 | rs9296404 | chr6:42925803 | GNMT | chr6:42928500-42931617:+ | -0.45 | -8.71 | 9.36E-14 | Plasma homocysteine levels (post-methionine load test) |
| THYM | cis | rs9296404 | 1 | rs9296404 | chr6:42925803 | PEX6 | chr6:42931613-42946981:- | 0.7 | 8.63 | 1.41E-13 | Plasma homocysteine levels (post-methionine load test) |
| THYM | cis | rs9473555 | 1 | rs9296616 | chr6:49414235 | CENPQ | chr6:49431096-49460820:+ | -0.23 | -4.18 | 6.53E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9296616 | chr6:49414235 | MUT | chr6:49398994-49431031:- | 0.28 | 4.37 | 3.17E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9296617 | chr6:49428360 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.35 | 3.4E-5 | Folate pathway vitamin levels |
| THYM | cis | rs929843 | 1 | rs929843 | chr16:70045748 | PDXDC2 | chr16:70010210-70099851:- | -0.56 | -5.28 | 8.06E-7 | Menarche (age at onset) |
| THYM | cis | rs2273 | 1 | rs9307050 | chr4:76905649 | NAAA | chr4:76831809-76862166:- | -0.46 | -4.92 | 3.56E-6 | Longevity |
| THYM | cis | rs9309473 | 1 | rs9309473 | chr2:73743982 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.49 | 2.03E-5 | Metabolite levels |